Science & technology | Livers, bacteria and alcohol

Bugs in the system

What really causes hepatic cirrhosis?

LIVERS and alcohol do not get on well together. That is well known. But precisely how alcohol destroys the liver of someone who drinks too much has been a mystery. Though alcohol (technically, ethanol—the type of alcohol that has two carbon atoms and is produced by yeast fermentation) wreaks some damage directly, experiments suggest this is by no means the whole explanation. The serious and irreversible harm of cirrhosis seems to have another cause, hitherto unknown. Now, though, perhaps it has been unmasked. For a team of medical researchers led by Bernd Schnabl of the University of California, San Diego suggest the culprit is alcohol’s effect on the gut, and the bacteria therein.

This article appeared in the Science & technology section of the print edition under the headline “Bugs in the system”

The right way to do drugs: Legalising cannabis safely

From the February 13th 2016 edition

Discover stories from this section and more in the list of contents

Explore the edition

Discover more

Dr Dorothy Bishop.

Elon Musk is causing problems for the Royal Society

His continued membership has led to a high-profile resignation

Legal Amazon preservation area borders the field for soybean planting.

Deforestation is costing Brazilian farmers millions

Without trees to circulate moisture, the land is getting hotter and drier


Robot mixing at Toyota Research Institute.

Robots can learn new actions faster thanks to AI techniques

They could soon show their moves in settings from car factories to care homes


Scientists are learning why ultra-processed foods are bad for you

A mystery is finally being solved

Scientific publishers are producing more papers than ever

Concerns about some of their business models are building

The two types of human laugh

One is caused by tickling; the other by everything else